Some medications are developed to lower glucose in the body over time. That can achieve an important balance for critical clinical parameters. The phenomenon can be observed in electronic health records obtained for these patients too. That offers direct evidence as to the effectiveness of the medication over time. That has bolstered these claims based studies of oral medication as well. Patients have shown signs of recovery that need to be evaluated and treated by medication.
Key Takeaways:
- todays databases do not collect the information it claims it does.
- it was needed to find out what was not being collected
- with a larger database they were able to identify the missing information
“In the context of pharmacoepidemiologic research on diabetes therapy, choosing appropriate comparison groups paired with a new user design and 1:1 PS matching on many proxies of diabetes severity and duration improves balance in covariates typically unmeasured in administrative claims datasets, to an extent that residual confounding is unlikely.”